HONG KONG -- High, high up, on the 118th floor of Hong Kong's tallest building, a deep concrete pit awaits mutation into a swimming pool.
Therein, he considers the concrete example of a mutation with selective advantage s = 1% spreading along a continuously occupied shoreline.
In contrast, mutations that concern timestamps present silent failures only in cases in which the concrete element is removed (mutations TSEmpty and TSRemove).
An in-depth understanding of these genomic regions, for instance by defining the selected phenotype and underlying mutations, may provide concrete evidences for explaining parallel adaptation to different selection regimes.
And at the far end of this spectrum, writing events in a particular individual are defined in a perfectly concrete manner these are the particular mutations occurring in the individual.
The concrete shape of fitness distributions of spontaneous mutations varies between species and even within the same species on different parts of DNA [ 18].
Instead, a figure of a protein with parallel mutations can be provided as a concrete biological example of the phenomenon.
The concrete goals of genetic testing and appropriate measures for identified mutation carriers are to identify these women and include them in surveillance programs enabling early detection and/or prevention of the occurrence of breast/ovarian cancer.
Cancer treatment requires modulation of concrete targets, which can be compromised by the compensatory mechanisms and/or mutations (Stelling et al, 2004; Kitano, 2007).
In order to evaluate whether cancer mutations perturb signaling networks, we initially developed a classification system with concrete types of NAMs.
