Furthermore, we explore the use of concordant matepairs to identify heterozygous and homozygous events and control the false discovery rate via a corrected P-value.
One promising avenue for further improvement is the use of concordant matepairs to identify false-positive clusters: if only a few discordant matepairs support a cluster, while many concordant ones contradict it, the cluster is likely to be a false positive.
We used separate generalized linear mixed-effect models, with admitting hospital as a random effect, to examine associations between patient race and the receipt of guideline-concordant antibiotics, ICU admission, use of mechanical ventilation, use of vasopressors, LOS, and 30-day mortality.
We used separate generalized linear mixed-effect models, with admitting hospital as a random effect, to examine associations between patient race and the receipt of guideline-concordant antibiotics, ICU admission, use of mechanical ventilation, use of vasopressors, hospital LOS, and 30-day mortality.
One significant finding in our study related to the use of antibiotics concordant with the American Thoracic Society / Infectious Diseases Society of America community-acquired pneumonia guidelines.
Furthermore, the results show that there were further aspects of practice that were concordant among surgeons, such as use of early CT and agreement that infected necrosis should be treated surgically.
There were no significant differences between whites and blacks in regards to obtaining blood cultures prior to antibiotics (OR 0.69, 95% CI 0.32 1.47), oxygenation assessment within 24 hours (OR 1.61, 95% CI 0.85 3.04), or use of guideline concordant antibiotics (OR 0.86, 95% CI 0.62-1.71).
Our study aimed to provide more information for the future research and clinical use of the concordant-discordant framework by (1) increasing the number of conditions that can be characterized as concordant or discordant with diabetes, and (2) examining the number of care goals that are shared between concordant and discordant conditions.
The major goal of this study was to provide more information for the future research and subsequent clinical use of the concordant-discordant framework by (1) increasing the number of conditions that can be characterized as concordant or discordant with diabetes, and (2) examining the number of care goals that are shared between concordant and discordant conditions [ 7].
