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However, all the candidate unigenes demonstrated a concordant trend of change for both DGE and qRT-PCR results, indicating that our results were reliable.
The concordant trend of increased risk of GD variants for developing MSA in each of the three series utilized in this study (Japanese, European, and North American) strengthens our conclusion and makes a bias of stratification unlikely.
Gene set analysis: HTSanalyzeR implements two approaches: (i) hypergeometric tests for surprising overlap between hits and gene sets, and (ii) gene set enrichment analysis to measure if a gene set shows a concordant trend to stronger phenotypes.
Evidence for aortic cell senescence in Ang II-infused Col1a1 r/r mice was also evident by upregulation of p16INK4A (P = 0.036 Fig. 3F), with a concordant trend for p21CIP1 (P = 0.235, Fig. 3F).
If the correlation test p value is significant but the binomial test is not, it suggests that although there is concordant trend in p values between the two groups, there are not enough statistically significant genes in both sites for binomial p value significance.
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The overall concordant trends between the measured δCa, the eustatic sea level curve, and the sizes of the flooded continental area throughout the Early Cretaceous Eocene, point to a linkage between the Ca isotopic composition of paleoseawater and long-term paleogeographic and oceanographic changes.
UMLR result was concordant with trend test (OR > 1; p < 0.05 for both cohorts).
Worse OS was demonstrated for qPCR [HR = 2.09 (1.27–3.42); P = 0.004], with a concordant nonsignificant trend for FISH/blot.
The gradual decline in needlestick injuries prior to and following regulatory change in Ontario is concordant with trends observed in British Columbia, Canada where regulation was established in 2007 [ 10].
Univariable and multivariable logistic regressions found associations between each background characteristic and non-participation versus participation in the VIP that were concordant with participation trends (Table 3).
This trend was concordant with the findings of a study among an Italian population, 12 which assessed the time to acquiring tolerance to cow's milk.
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