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There were 577 (32%) individuals with concordant positive results and 508 (28.2%) had concordant negative results.
Those with concordant negative or positive results were considered HIV negative or positive, respectively.
Among 30 controls where both tests were done, none was concordant positive, 6 (20%) were concordant negative, while 24 (80%) were positive by serology alone.
The high rate of TB in individuals with concordant negative TST and EC responses could be driven by concurrent HIV infection [19] that may affect the performance of the ELISPOT [12].
Of 48 cases in whom both serology and IHC were performed, 25 (52.1%) were concordant positive, 2 (4.6%) concordant negative, while remaining 21 (43.5%) were positive by one of the two tests.
Concordant negative couples comprised 55% of the sample, 23% were discordant, and 22% were concordant positive.
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Concordant negatives were tested with the sensitive Murex enzyme immunoassay (Abbot, Dartford, UK).
Another study concluded that men were four times more likely than women to introduce HIV infection in concordant-negative couples [45].
As expected, the concordant-positive group was associated with a significantly shorter OS when compared with the concordant-negative group.
The concordant-positive group was associated with a significantly shorter OS compared with the concordant-negative group (HR = 4.7, 95% CI, 2.1 to 11; P = 0.0002).
Next, we performed Kaplan-Meier analysis to evaluate OS for the patients in discordant high group or the discordant low group in comparison with patients in either the concordant-positive group or the concordant-negative group.
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