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The concordance score demonstrated predictive validity, as patients whose treatments were concordant with their goals had more confidence and less regret with their decision compared to those who did not.
Second, a study comparing the content and tasks as well as test performance on the two tests should be required research before test agencies develop concordance score tables and use the tables for making decisions and portability of tests and scores.
We ranked the 9981 proteins according to the concordance score for the 678 known-target drugs.
Our mutual concordance score is also more powerful, since it pools information from many miRNA-target pairs to find highly correlated individual pairs.
A combined concordance score of 90% (p<0.0001, binomial test) was attained in training trials on laboratory diet (termed Diet L).
We then identified miRNA-target mRNA pairs showing the highest difference in mutual concordance score between AD and control (which, again normalized by <img src="http://journals.plos.org/plosone/article/asset?id=info?doi/10.1371/journal.pone.0008898.e177.PNG" class= inline-graphic"/>, we called differential mutual concordance score).
Similar(19)
Instead, the genome-wide concordance scores describe the importance of the protein to in the activity of the drug, and proteins with large concordance scores could be hypothesized as potential drug targets.
A genome-wide map of predicted biological fingerprints is comprised of the 9639 concordance scores (http://bioinfo.au.tsinghua.edu.cn/drugCIPHER/Drug_biological_fingerprints.rar).rar
For a query drug, each protein in the PPI network is assigned three concordance scores based on the different regression models.
The genome-wide concordance scores produced by drugCIPHER-MS implied the importance of each protein in the biological activity of a given drug, therefore they can be viewed as a drugs biological fingerprint.
19 RCR produces richness and concordance scores (see Methods 6).
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