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The concordance pattern was evaluated using both the unweighted and the weighted kappa statistics; the strength of agreement was as follows: <0.00 = poor agreement, 0.00 0.20 = slight agreement, 0.21 0.40 = fair agreement, 0.41 0.60 = moderate agreement, 0.61 0.80 = substantial agreement, and 0.81 1.00 = nearly perfect agreement [ 13].
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For instance, breakdown in phylogenetic concordance patterns has been argued to be partly the result of genetic introgression and hybridization across different fig species [ 8, 38, 40].
Interestingly, although we found concordance between dieldrin and Ni2+ and between diazinon and dieldrin for the ionotropic glutamate receptors, the correlation was much poorer between dieldrin and Ni2+; this points out that the concordance patterns between any two agents can involve sets of genes different from those generating the concordance between one of those agents and a third compound.
Such concordance in pattern and tempo of diversification suggests that global-scale changes have shaped the histories of many diverse groups of taxa [ 32].
Finally, concordance of patterns of effects between different agents was evaluated by linear regression analysis.
A striking concordance between patterns of gene expression that have classically been associated with cancer and the range of genes induced by HIF activation in cultured cells was noted [ 5].
The concordance between patterns involving the 123 gene duplicates in that study, and the 1211 plus mito-sensitive nuclear genes in this study, both in terms of chromosomal distribution away from the X, and in terms of tendency for testes-specific expression, is strong; and supports the idea that male-specific mitochondrial mutation loads might underpin these patterns.
131I-MIBG and 111In-pentetreotide tumor uptake pattern concordance (or discordance) for each subject is given in the first column of Table 2. Table 3 provides a summary of individual lesion MIBG and pentetreotide uptake status for these six subjects.
In the solid pattern concordance was found in five cases and discordance in three.
The same was done for drinking pattern concordance but with binge drinking instead of frequent drinking.
Recently, however, it has been reported that more general quantile-based procedures yield much better concordance with expression pattern values obtained by qRT-PCR [ 40].
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