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To elucidate the concordance of human papillomavirus (HPV) genotypes between the mother and her newborn and to identify risk factors for the vertical transmission of HPV.
Next we examined the concordance of human and murine gender biased genes in the kidney.
The use of animal studies to identify human carcinogens is supported by observations about the overall concordance of human studies with animal tests.
Collectively, the broad concordance of human and murine datasets indicates conservation of CIS mutational function across species, and substantiates the concerted action of CIS network genes as a tumourigenic process promoting cell proliferation and inhibiting neuronal differentiation.
Overall, the concordance of human and laboratory animal studies and the spectrum of effects (from biomarkers to frank expressions of disease) strongly support the conclusion that TCE causes immunotoxicity, particularly in the form of autoimmune disease and a specific type of severe hypersensitivity skin disorder, with more limited evidence for immunosuppression.
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The high degree of concordance with human QTL demonstrates usefulness of our approach in humans.
Birth order, delivery route, and concordance in the transmission of human immunodeficiency virus type 1 from mothers to twins.
Type 16 was detected in metastases from 4 patients; complete concordance for the presence of human papillomavirus in primary and metastatic disease was noted.
The results are in concordance with most studies of human lymphoid neoplasia that revealed relative sensitivities of 100% and specificities of 97% to 100% for MCA compared to PAGE [ 20, 22].
These points of concordance between human and model TOJ performance suggest that the brain indeed integrates across the full posterior probability distribution.
This lack of concordance between human and animal studies does not provide evidence to support an argument for formaldehyde-induced hematotoxicity, unlike benzene and other leukemogens that show concordance between animal and human data (as discussed in Section 5.3.3).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com