Concordance was calculated by the proband method.
The overall concordance was calculated as the percentage of the 1st and 2nd compilations for each item (Table 4).
Relative genotype concordance was calculated as follows: In each S-WGA array data set, genotype concordance rate was calculated by chromosome, and then concordance rates were divided by the average concordance rate (similar to per-chip normalization).
In this group lowest concordance was observed for Coagulase-negative staphylococci identification 65/82 (79%), whereas, highest concordance was calculated for Streptococcus pneumoniae 81/82 (99%).
On pathogen level the species specific overall concordance was calculated as the ratio of the sum of positive and negative identical results to the entire number of results.
For the analysis of mono- or polymicrobial infections concordance was calculated as the sum of positive identical results to the entire number of results.
Concordance was calculated using Cohen's Kappa.
Probandwise concordance was calculated by zygosity for anxiety and depression.
Test concordance was calculated using the Kappa coefficient statistic.
