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The striatal-to-cerebellar ratio (SCR) of 11C-raclopride uptake obtained using the PET template was in good agreement with the MRI-based image processing method, yielding a Lin's concordance coefficient of 0.87.
The relationship of estimated versus observed skip length had a coefficient of determination of 0.97, which was confirmed by the value of the enhanced Wilmott concordance coefficient of 0.92, indicating good agreement.
The W Kendall test scored a concordance coefficient of 0.81 (p < 0.01).
The high interlaboratory concordance coefficient of DDE serum values suggests valid estimates.
The original scaling values showed Kendall's concordance coefficient of W = 0.446 (p < 0.0005, N = 394), meaning that a significant trend of positive agreement in the ranking of stressful events was observed in this sample [ 33].
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The results of two independent methods were in good concordance: coefficients of linear regression and correlation (Pearson r) were equal to 0.84 and 0.80 respectively (complete RT-qPCR results are in Additional file 2).
Comparing the MR and PET template-based spatial normalization methods, there was a high degree of concordance between the measured tissue concentrations in the caudate nucleus and the putamen in MNI space with a Lin's concordance coefficient (ρc) of 0.87 including an upper one-sided 95% confidence interval of ρc = 0.93 and a lower one-sided 95% confidence interval of ρc = 0.79 [15].
A concordance coefficient with value of 1 indicates a perfect agreement, −1 indicates a perfect disagreement, and 0 indicates no agreement.
In the same way, the concordance coefficient between each of the 100 classifications and the final assignment was 0.62 (95% CI [0.61-0.63]) on average.
To avoid such an important bias, we tested intra-rater reliability by comparing respective concordance coefficients instead of direct comparison of visual estimations.
Fifth, the comparison of concordance coefficient between G1 and G2 might have been influenced by the dynamic range of MBF and MFR.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com