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The use of the 9c ER to classify gastric cancers as ICM-DNA aneuploid (category definition D) did not increase the percentage of concordant cases between the two methods above the concordance achieved using Hedley's classification.
However, the relatively high concordance achieved in this benchmark investigation is only the beginning of exploring cross-platform consistency because it is based on two microarray datasets generated on identical biological samples using different platforms, i.e., this investigation is mainly focused on a technical platform comparison.
If we only considered those patients colonized by A. baumannii and P. aeruginosa, the percentage of concordance achieved 69%.
To check reliability, genotyping was randomly repeated in 10% of samples, with 100% concordance achieved for all results.
For chromosomes 3, 6 and 28, the genotype correlation and concordance achieved by three different imputation packages (Minimac, FImpute and IMPUTE2) are shown in Fig. 3.
Of the 107 renal cortical neoplasm biopsies for which a FISH-based classification was obtained (bp-FISH), the optimum concordance achieved using the refined tree was 79% (84/107, Table 3).
Similar(53)
Immunostained TMAs were examined independently by two pathologists and a high degree of inter-observer concordance was achieved (r>0.7, p<0.0001) as well as intra-observer concordance on different sessions (r = 0.79, p<0.0001).
Notwithstanding these limitations, concordance levels achieved for pH, CO2 and lactate values reported across collection and analysis techniques were supportive of the fact that the type of analyzer used did not influence results significantly.
If less than 80% concordance was achieved between evaluations, the entire batch of slides was re-read.
Statistical significance for Ptgds, Cldn5, Qprt, and Tmem132A was confirmed by real-time RT-PCR (p<0.05; Table 2); and while directional concordance was achieved for Fmod, Ifi27, Fam69b and Esam, changes in expression were not statistically significant.
Concordance was achieved in all cases.
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