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Finally, patients may not have received any other experimental medication within 30 days (and at least five drug half-lives) prior to inclusion in this study, and cannot concomitantly take mercaptopurine.
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Concomitantly, taking to the seas on rafts and boats is on the increase.
Individuals concomitantly taking lobeglitazone and a CYP3A4 inhibitor may experience some adverse effects secondary to increased systemic exposure to lobeglitazone.
Instead, the risk greatly increases whether the patient is concomitantly taking steroid and/or immunosuppressant agents.
Four patients with severe persistent asthma were concomitantly taking an oral corticosteroid (prednisolone), and other patients were taking oral corticosteroids as needed at the time of attacks.
Patients who had received other investigational drugs within the preceding 30 days or were concomitantly taking other investigational drugs were also excluded from study participation.
IP-10 was measured in the blood and urine concomitantly taken from children who were prospectively enrolled with suspected active TB, with or without HIV infection.
Our dating approach allowed us to estimate that the split of the two most divergent mitochondrial phylogroups occurred 0.32 Myr ago and that the subsequent divergence of the two pairs of lineages concomitantly took place at around 0.23 Myr ago.
26 Based on these findings, reducing the dose of saxagliptin to 2.5 mg once daily for patients who are concomitantly taking ketoconazole or another strong CYP 3A4/5 inhibitor is recommended.
1 Dose adjustment to 2.5 mg is also recommended for patients who are concomitantly taking ketoconazole or another strong cytochrome P450 (CYP) 3A4/5 inhibitor (eg, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ritonavir, saquinavir, or telithromycin).
Older age, yellow and red triage, higher number of concomitantly taken drugs, and previous attendance in ED for the same ADR were significantly associated with an increased risk of hospitalization.
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