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Furthermore, the considerably 'off on' fluorescence response concomitantly led to the apparent color change from colorless to brilliant yellow, which could also be identified by naked eye easily under UV lamp.
Depletion of EWS/WT1 by two independent WT1-siRNAs concomitantly led to approximately 60% decrease in the ENT4 transcripts (Fig. 4C), further supporting the direct transcriptional regulation of ENT4 by EWS/WT1.
Finally, the increase in hpmKIlox mRNA concomitantly led to an increase in cell surface levels of β1 integrin-associated α subunits on hpm keratinocytes (see Figure S2 in Supporting Information).
We found that overexpression of a dominant active AKT construct in NCI-H929 cells dramatically reduced miR-29b levels and concomitantly led to Sp1 upregulation.
Development initiatives in the 1930s-1970s attracted people to Bombas who provided additional labor, but concomitantly led to more opportunities being established outside the territory and to emigration of inhabitants, particularly younger ones, in search of a better life.
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FtsY-depletion inhibits ribosome targeting [14] and concomitantly leads to specific inhibition of membrane protein synthesis.
In addition, data suggest that the accumulation of drug resistance mutations can reduce the replication capacity of HIV-1 [20], which could concomitantly lead to reduced virulence.
In particular, many studies have shown that receptor stimulation by an agonist concomitantly leads to receptor signaling and redistribution of receptor molecules away from the cell surface (for review see [2] [3]).
GPC is produced from the breakdown of the membrane phospholipid phosphatidylcholine (PtdCho) in a 2-step reaction mediated via phospholipase A and lysophospholipase, which concomitantly leads to the formation of free fatty acids (FFAs).
This structure together with that of the raloxifene (antagonist) complex presented concomitantly [ 12] led to a structural proposal to explain agonism and antagonism in NRs.
Concomitantly, this treatment also led to a reduction in the expression of the cell survival and proliferation up-regulator transcription factor c-myc.
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