Previous studies using the plus-maze discriminative avoidance task (PMDAT, which assesses memory and anxiety concomitantly) indicated that the effects of BDZs on anxiety and acquisition are related to each other.
Moreover, 5-aza-dC pretreatment partially restored HHIP expression and leukemic cell proliferation on coculture was concomitantly reduced, indicating that aberrant reduction of HHIP expression is associated with the leukemic cell-supporting activity of BM stromal cells.
However, the late SG differentiation marker melanocortin-5 receptor (Mc5r) (Chen et al, 1997; van der Kraan et al, 1998) was not upregulated concomitantly (Fig 3C), indicating a disturbance in late differentiation or maturation of sebocytes.
Transversion and transition rates increase concomitantly with genetic distance, indicating that there is little or no saturation.
It has been shown that NO improves the effect of the ischemia induced in liver, kidney and testicular tissue as measured by damage markers and concomitantly increased Shh expression indicating that NO acts via increase of Shh expression in ischemic tissue [36] [38].
The phosphorylation levels of ArcB decreased concomitantly (Fig. 4g), indicating that the phosphorylation of PpPRR2 RLD is due to phosphotransfer from ArcB.
The IgG and IgA secretion in response to mitogenic stimuli is severely impaired and does not normalize concomitantly with serum Ig, indicating a possible impairment in the isotype switching mechanism.
Concomitantly, this observation indicates, however, that selective targeting of CNS B cells, which may be desirable in some settings to reduce systemic side effects, may not be feasible by this approach.
Interestingly, parasites overexpressing ODC showed an increased resistance to the antimonial drug Pentostam, concomitantly with resistance to APA, indicating a role for ODC in the development of Leishmania drug resistance (see below) [ 86].
