Typically, patients with cancer receive a high number of drugs concomitantly, including cytotoxic agents, hormonal agents, targeted agents, and supportive care agents among medication prescribed to treat comorbidities.
For example, 3q gain was detected in 17% (1 out of 6) VSCC compared with 70% (37 out of 53) of the CxSCC series analysed concomitantly (including 60%, 6 out of 10 of the Stage I tumours) and 100% (9 out of 9) of the Stage I and II cervical tumours investigated by Wilting et al (2006).
All potential predictors were concomitantly included in the multivariable logistic regression model, which was reduced using forward and backward stepwise selection taking into account the significance of the likelihood-ratio test (p ≤ 0.05 for inclusion and p > 0.051 for exclusion).
The anti-apoptotic neuroprotective properties of EPO in ischaemic tissues may occur concomitantly with angiogenesis including promotion of revascularisation [5], [6] and microvascular remodelling [7].
Additionally, TCM doctors commonly prescribed multiple CHM concomitantly; 5.4 CHM, including SH and/or HF, were used in on average in one prescription.
Thus, its application could potentially be more appealing to most conventional research laboratories, especially those with radioactive safety concern and/or limited labor for conducting concomitantly several experiments including those requiring tedious subtractive investigations.
The hepatitis B panel is complemented by third generation assays for anti HCV and anti-HIV that concomitantly detects HIV-1 (including group O) and HIV-2.
The hearts of H/M- Sod2−/− mice showed an increased susceptibility to ventricular arrhythmias during rapid ventricular pacing, concomitantly with ECG changes including prolongation of the QRS and QT intervals and a flattening of the J wave.
Only data from nonrepeat isolates from patients > 17 years of age, located on ICUs, and derived from antibiotics concomitantly tested were included in the analysis.
38, 43 The pharmacological interactions with fluconazole include concomitantly administered phenytoin, rifampin, rifabutin, cyclosporin A, and possibly some of the protease inhibitors.
Fibrates are well tolerated in most cases concomitantly with occasional adverse reactions including muscular toxicity, which is enhanced by the combination with statins.
