In fact, bevacizumab added to chemotherapy did significantly prolong the survival of the mice compared with chemotherapy alone; the survival of mice receiving bevacizumab only after chemotherapy (MST 56 days, ILS 124%) was not different from mice treated with bevacizumab concomitantly with PTX+DDP and continued (MST 59 days, ILS 136%) (detailed results in Supplementary data, Table 4).
These epidemiologic studies suffer from lack of randomization and the resulting potential for unintentional channeling biases, from lack of rigorous documentation of drug actually taken and of nonprescription drugs administered concomitantly, and from dependence on diagnoses defined to meet coding requirements for insurance payments, without supporting documentation or detailed event descriptions.
Detailed information about the patients with invasive candidiasis was retrieved from the hospital's medical records and from the hospital's microbiology laboratory as not all these patients were concomitantly in neutropenia and/or underwent HSCT during their hospitalisation with invasive candidiasis and were, therefore, not recorded in ONKO-KISS.
Other antibiotics prescribed concomitantly 7. Other drugs prescribed concomitantly 8. Details of gentamicin therapy, including dosing regime and duration 9. Length of stay in hospital 10.
We surmise that IRE1 assemblies that are obligatorily larger than a dimer are necessary to concomitantly engage both splice sites (see Discussion for details).
In details, the aES makes the migration possible, concomitantly with the differentiation of spermatids across the seminiferous epithelium.
However, it has not been investigated in detail how EC division proceeds in a dynamic environment, in which lumen formation and cell rearrangements occur concomitantly and vessel integrity has to be maintained.
Cell viability concomitantly decreased.
Concomitantly, neurogenesis and neuroplasticity fall significantly.
Concomitantly, cytoskeletal F-actin structures depolymerize.
Concomitantly, adenosine release increased by fivefold.
