First, MDD implies that all dispensable tablets which should be ingested concomitantly are delivered in machine-dispensed unit bags.
Radiotherapy was delivered concomitantly with either 5-FU or S-1.
Furthermore, liver metastases consisted solely of neuroendocrine-differentiated cells, with no evidence of non-neuroendocrine cells despite both cell types being delivered concomitantly.
However, this technique is promising in the elderly, since a single fraction therapy delivered concomitantly with surgery may avoid the inconvenience of several weeks of daily therapy.
Results of the present study confirmed the similar efficacy between FEC100 and a regimen including an anthracyline delivered concomitantly with a drug interfering with tubuline.
The Herskovic CRT regimen was based on four CDDP/5FU chemotherapy courses, which were delivered concomitantly with 50 55 Gy radiotherapy (weeks 1 5).
However, there are well-described fractionated regimens that would serve as very useful therapeutic models in which variable numbers of treatment fractions could be delivered concomitantly with a putative radiosensitiser (reviewed in Lester et al, 2006).
It is reasonable, therefore, that increased levels of soluble HS proteoglycan delivered concomitantly with certain growth factors would lead to enhanced growth factor activity in a physiological manner and be of value in wound management and healing.
The CRT regimen based on the CDDP/irinotecan chemotherapy combination has been recently reported in a phase II multicentric trial and consisted of eight chemotherapy courses delivered concomitantly with 50 55 Gy radiotherapy (courses five to eight).
Both treatment regimens, which will be administered concomitantly with daily triptorelin acetate, will be delivered subcutaneously at approximately the same time each day; study participants will be instructed on how to self-administer treatment, with the first dose to be administered at the clinic under supervision.
