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Often, genes that move away from the lamina are concomitantly activated; many others, however, remain inactive yet become unlocked for activation in a next differentiation step.
Concomitantly, activated macrophages and sinusoidal endothelial cells secrete the prothombinase fibrinogen-like protein 2 (FGL2), initiating fibrin matrix formation.
Concomitantly, activated RhoA may favor peroxisome association with the actin cytoskeleton possibly by recruiting Rho kinase (ROCKII).
The induction of NF-κB and AP-1 transcription factors is concomitantly activated after 3 h of infection of HT-29 cells with EDL933.
We found that FK866 was toxic to PBLs when these were concomitantly activated with mitogens [phytohematoagglutinin-P (PHA), or concanavalin A (Con A ], while unstimulated cells were mostly unaffected (Figure 1B).
These results suggested implication of the Homer-Shank3 complex dissociation, rather than an effect of Homer1a per se, in the inhibition of NMDA-R by mGluR1a, when both receptors were concomitantly activated.
Similar(47)
In summary, these data demonstrate that EtOH suppresses mTORC1 activity and complex formation, while concomitantly activating AKT (at both Thr308 and Ser473) and mTORC2 assembly in a manner similar to the feedback observed in rapamycin treatment.
It is unlikely that indirect activities (e.g., activation of certain ethanol-responsive transcription factors that concomitantly activate certain miRNAs and respective target genes) are responsible for such over-targeting of upregulated mRNAs by a majority of the upregulated miRNAs.
Binding of a Flp monomer to DNA concomitantly activates the scissile phosphate [30].
By uncoupling peroxisomes from microtubules, RhoA-GTP may concomitantly activate ROCKII, a serine/threonine kinase acting immediately downstream of RhoA.
Protein misfolding concomitantly activates PERK and IRE1 and has clouded insight into their contributions toward life or death cell fates.
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