Another interesting concept is epithelial-mesenchymal transition (EMT), a process by which cells lose their polarized epithelial structures and concomitantly acquire a migratory or mesenchymal phenotype.
For instance, the downregulation of cell cell adhesion is a hallmark characteristic of epithelia mesenchymal transitions (EMT), a process by which cells lose their polarized epithelial phenotype and concomitantly acquire a migratory or mesenchymal phenotype [ 1].
Under this condition, Mtb stopped replicating, lost acid-fastness, accumulated triacylglycerol (TG) and wax ester (WE), and concomitantly acquired phenotypic antibiotic-resistance.
In addition, studies in pancreatic cancer found that therapy-resistant tumor cells had concomitantly acquired markers associated with stem-like cells and changes related to EMT, such as vimentin upregulation and E-cadherin downregulation.
In a recent work it has been shown that in response to barrier disruption, keratinocytes upregulate MHC-like ligands, such as Rae-1 (in mice) or MICA (in humans), which bind to the activating receptor natural killer cell lectin-like receptor 2D (NKG2D) on intraepithelial γδ T cells, eventually inducing TH2-driven responses against concomitantly acquired antigen [38].
Yet, internalizing GLUT4 myc did not reach this sub-compartment and concomitantly it did not acquire insulin responsiveness.
On the other hand, a subset of MBs, and/or a subset of cells within a given tumor, express high levels of MYC and acquire a concomitantly increased JAG2 protein level, which likely alters the fine-tuned NOTCH signaling cascade.
Validity of results is ensured by concomitantly testing the acquired sample for representativeness by statistical inference via bootstrap analysis.
ASTER and Landsat Thematic Mapper (TM) images were acquired concomitantly and classified following similar methods to identify water bodies for three color classes and a range of sizes.
While the SFD survey was delayed, and some seismic acquisition ended up being acquired concomitantly, the exploration strategy adopted envisioned subsequent seismic acquisition, in order to produce a detailed structural map of the anomalies indicated by the initial SFD survey (Khan 2013).
Stigmatic receptivity was acquired concomitantly with the secretion of AGPs.
