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Several possible roles were proposed for DNA curvature and concomitant sequence periodicity in prokaryotes but its exact biological function is not well understood.
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This is a consequence of discarding reads that are considered to be redundant and the concomitant sequencing error removal.
Still, other studies have capitalized on the concomitant sequencing of host and associated microbes and reported the presence of these microbes in conjunction with the eukaryotic sequencing project (Chapman et al. 2010; Gillespie et al. 2012).
The flaR gene and the dpp operon show high similarities in GAS and SDSE (Additional file 5), with concomitant sequences observed only in GAS and SDSE but not in other streptococci (data not shown).
High-throughput tag-sequencing for digital gene expression (DGE) analysis is a powerful, recently developed tool that allows the concomitant sequencing of millions of signatures to the genome, and identification of specific genes and the abundance of gene expression in a sample tissue [ 22].
In contrast with uncomplicated malaria, parasite clearance times for severe malaria are difficult to compare when different drug regimens (concomitant and sequence therapy) have been used.
An EST collection typically contains redundant, as well as partial sequences of the same transcript (mRNA) concomitant with sequencing errors due to the single pass nature of the method.
The biosensor was also capable of discriminating single-nucleotide difference among concomitant DNA sequences and performed well in spiked cell lysates.
The new generation of NGS sequencers has made it possible to increase the number of bases sequenced per run with a concomitant decrease in sequencing costs, due to technological improvements.
The predictive features of the k-mer analysis are therefore relying on a secondary but concomitant degradation of sequence quality and distribution.
Our analyses confirm that these human genes have duplicated unusually rapidly within the last 3 MY, with concomitant and substantial sequence diversification resulting from adaptive evolution.
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CEO of Professional Science Editing for Scientists @ prosciediting.com