Previous findings from the Watt group in which MYC is targeted to basal keratinocytes has, in contrast, shown that activation of MYC promotes an increase in the number of proliferating keratinocytes concomitant with promotion of terminal differentiation of epidermal stem cells [ 89].
We also anticipate a concomitant benefit on childhood obesity because promotion of mothers' healthy lifestyles can help their young children establish healthy eating behaviors and physical activity, which are major factors in preventing childhood obesity.
However, chronic oxidative stress down regulates ALDH1A1 and ALDH2 with a concomitant increase in HNE-induced toxicity and promotion of the senescence phenotype.
Tellingly, the knockdown of Tfam with RNAi can suppress CycD/Cdk4's detrimental effects on both lifespan and neuronal death, implying that CycD/Cdk4's pathological consequences are mediated through its promotion of mitochondrial biogenesis and the concomitant increase in ROS.
Promotion of plant growth by P. bilaii inoculation without a concomitant increase in the P content of these plants has been found in several studies [22, 24, 38 41], showing that the P. bilaii root growth increase may be related to mechanisms other than P uptake, such as phytohormone production or other possible mechanisms against abiotic stresses [42 44].
These reports point to a dual beneficial function of statins in anticancer therapy, that is, the promotion of anticancer drug-induced killing of malignant cells and concomitant protection of normal cells.
Genes with this profile may be involved in the promotion of cell death in response to E2F1 activation, which is blocked by concomitant PI3K activation, tilting the balance towards proliferation over apoptosis.
The TP amplification is associated with concomitant overexpression of many angiogenic factors such as matrix metalloproteases (MMPs), interleukins (ILs), vascular endothelial growth factor (VEGF) etc., resulting in promotion of angiogenesis and cancer metastasis.
- and a concomitant openness about sex.
It is Cornerstone Promotion, not Cornerstone Promotions.
