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We found that, among protein enzymes involved in lipid metabolism, the lipogenic enzymes ACL and FAS were predominantly suppressed in both the WAT and liver in mice challenged by HFD feeding, in parallel with concomitant onset of hyperleptinemia.
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Using this strategy, we showed that whole brain dopamine, glutamate and GABA depletion are concomitant with onset of initial behaviour deficits.
A large proportion (92%) of the NP-C uncertain group had psychosis, with two patients also showing concomitant early-onset progressive cognitive decline.
The reconstructed paleoenvironmental evolution at the site captures the warm and humid conditions associated with GI-1, as well as the subsequent cooling concomitant with the onset of GS-1.
Concomitant with the onset of gastrulation, the increase in cell number slows as cell cycles lengthen.
Promotion of the hyperplastic switch is thought to be in part mediated by the growth/survival factor, IGF-II, as its expression is induced concomitant with the onset of β-cell hyper-proliferation [15].
H2B-eYFP expression is first observed at late HH stage 6 in the ECs within extraembryonic blood islands, the earliest discernable vascular structures in avian embryos [31], [32], concomitant with the onset of TIE1 mRNA expression (Fig. 1c and 2a).
Thus, bud formation is concomitant with dormancy onset [ 6- 8].
Concomitant with the onset of GC parallel fibers, PCs differentiate by completing their dendritogenesis.
The transgene expression of bigenic mice started roughly around birth (0mo) concomitant with the onset of CaMKIIα activity.
Our work shows that SOPE has undergone very rapid genome degeneration concomitant with the onset of host association.
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CEO of Professional Science Editing for Scientists @ prosciediting.com