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In the case of the former, the continuous appraisal of a drug's benefit-risk profile is highlighted by the present drive towards a shorter but more efficient pre-authorization drug development phase [ 2, 3] and the concomitant move towards progressive authorization, that is, authorization that allows earlier but limited release of a drug and license expansion is dependent on new data [ 4].
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As a result, force only affects directly the mechanical step in which the anticodon loops of the tRNAs move from the A and P sites to the canonical P and E sites of the 30S subunit, respectively, together with the concomitant movement of the mRNA with respect to the ribosome.
Below, it is formulated in a concomitant reference frame moving on the bore hole surface constraining the DS transformation.
Of the 46 patients with suspected PA eighteen patients did not participate due to another concomitant illness, they had moved or refused further investigation.
At the beginning of syringe resuscitation, aortic and vena caval blood was drained slightly during the suction phase and the blood moved to in both directions during the push phase; however, the dye transferred gradually from the vena cavae to arterial side while showing a concomitant to-and-fro movement of its own with the repeated piston movement.
As sulfation proceeded, a third zone (the sulfated zone) developed and the NSR zone moved downstream, with a concomitant decrease in both the OSC-only zone and global NOx conversion.
Regularly occurring periods of eye motility, and concomitant phenomena during sleep.
On the basis of analysis of foot plate angle and GM relative length as a function of externally applied moments, it is concluded that foot plate angle measurements underestimate angular changes at the talocrural joint when moving in dorsal flexion direction and overestimate them when moving in plantar flexion direction, with concomitant effects on triceps surae lengths.
During this process, one nucleus moves to a forming appressorium, concomitant with translocation of other nuclei to the conidium, followed by their autophagy-dependent disappearance.
Thus, LeBron has metaphorically grounded one foot in core values that evince themselves in disciplined teamwork and elevated on-court collaboration, while turning his gaze in a new direction, to his next challenge -- a move toward home along with the concomitant goal of bringing a long-awaited championship to Cleveland.
At t = 340 s the cell pulled on the trapped bead which consequently moved toward the cell and at t = 480 s we observe a relaxation of the force (bead moves away from the cell) with a concomitant increase of the curvature of the actin shaft (increased buckling).
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