Sentence examples for concomitant dose from inspiring English sources

With the second and third occurrences of grade 3 skin toxicity, cetuximab therapy may again be deferred for up to two consecutive weeks with concomitant dose reductions to 200 and 150 mg m−2, respectively.

AEs/ADRs were documented in terms of their nature, start time, start date, stop date, concomitant dose, seriousness, intensity, putative causality, other possible causes, treatment (if required), and outcome.

Although ropinirole may worsen pre-existing dyskinesia or increase the development of dyskinesia in patients with PD, dyskinesia can often be managed by decreasing the concomitant dose of levodopa.

In the case of a second occurrence of grade 3 skin toxicity, cetuximab therapy was delayed for up to two consecutive infusions with concomitant dose reductions to 400 and 300 mg m−2, respectively, which were permanent until completion of treatment.

For patients with Grade 4 neutropenia lasting 5 or more days or febrile neutropenia, the BMS-184476 dose was decreased by one level (dose levels −1 and −2 were 30 and 25 mg m−2, respectively) with a concomitant dose reduction in carboplatin of 50%.

The ability of fibrin-bound ephrin-B2 to act as ligand for endothelial cells was preserved, as demonstrated by a concomitant, dose-dependent increase of endothelial cell binding to engineered ephrin-B2 fibrin ephrin-B2 fibrintro.

Concomitant dosing of antiXa (laboratory) and ACT (Hemocron®) was conducted two times a day on the same sample throughout the ECMO period.

The α-helical content gradually increases upon increasing the TFE concentration from 0 to 25% and then reaches a plateau, while no concomitant dose-dependent increase in the content of β structure is detected (data not shown).

αSMA expression occurred in the treated cells with a concomitant dose-dependent production of TGF-β [ 36].

These changes displayed a close correlation with a concomitant dose-dependent enhanced density of mast cells and staining for hyaluronic acid.

ICI but not TAM inhibited ER-mediated gene transcription and resulted in a concomitant dose-dependent reduction in ERα levels, while having no effect on ERβ.