Many LMNA mutations have been linked to striated muscle disease where there is progressive weakness of skeletal and cardiac muscle and often concomitant cardiac conduction system disease.
Attention Process Training-II: A program to address attentional deficits for persons with mild cognitive dysfunction (2nd ed).. Wake Forest, NC: Lash & Associates.; APT-II], when applied in the context of a multiple baseline ABA design, would improve the attention abilities of RW, a patient with mild conduction aphasia and concomitant attention and working memory deficits.
An electrocardiogram recording was repeated at all visits if the pretherapy/entry QTc was ≥ 500 ms or if the subject was taking a concomitant medication that affected cardiac conduction.
Demyelination and concomitant loss of axon insulation lead to the reduced motor nerve conduction velocity (MCV), increased central conduction time (CCT) and decreased amplitude of compound motor action potential (cMAP) in Twitcher mice (38, 39).
The concomitant 2∶1 heart block was very likely caused by conduction block in the ventricle due to extremely prolonged ventricular action potentials, similar to the suggested mechanism of 2∶1 heart block caused by another SCN5A mutation in a newborn[24].
This is concomitant to motor coordination impairment, disability and slowing of peripheral nerve conduction velocities (8, 9).
Drugs inducing the prolongation of AV conduction time nodes, β-blockers, calcium antagonists and possibly digoxin, have been proposed as useful concomitant medication during treatment with class IC antiarrhythmics.
Thus, the infra-Hisian conduction defect in α-MHC-LacZ- CTG 400 mice may be subtle and may become unmasked with concomitant medications which slow conduction, such as anaesthetics.
- and a concomitant openness about sex.
One such disorder, myasthenia gravis, stems from faulty nerve conduction.
