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Cutaneous laser stimulation selectively activates nociceptive afferents without concomitant activation of tactile afferents and, thus, allows for the selective experimental investigation of pain pathways19.
The peptide induced a rapid alkalinization of the culture medium of tobacco suspension-cultured cells and a concomitant activation of an intracellular mitogen-activated protein kinase [ 9].
The virus itself is internalized in clathrin-coated pits, but is unable to enter cells without concomitant activation of macropinocytosis, which facilitates the pH-activated escape from endosomes.
Concomitant activation of all command neurons thus perturbs normal activity and affects locomotion.
Given the progressive glial response to the neurodegeneration with concomitant activation and expression of neurotrophin which share survival activities of vessels, the responsive upregulation of the respective tyrosine kinase pathways appears as an epiphenomenon of the ongoing damage.
At 3 months, SOD activity was increased in LP and LPT islets with no concomitant activation of CAT and GPX.
Increased NAD+ levels and concomitant activation of SIRT1 might lead to reduction in several amino acids, which activates the AAR pathway in CD38-null mice.
Ox-LDL caused significant SR-A1 upregulation with concomitant activation of ERS as assessed by upregulation of GRP78.
Upon starvation or lysosomal stress, inhibition of mTOR and concomitant activation of the phosphatase calcineurin by TRPML1-mediated lysosomal calcium release induces TFEB dephosphorylation.
Loss of dco in the wing disc results in a dramatic reduction in expression of the caspase inhibitor DIAP1 and a concomitant activation of caspases.
Nitrites possibly work by stimulating the release of nitric oxide and the concomitant activation of cyclic GMP, although it is unclear whether this mechanism is responsible for their intoxicating properties (Balster, 1998).
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