However, conclusively identifying the relevant gene(s) from the many within each large region has proven to be more difficult than anticipated.
Evans also recommended that Australia perform flybys or naval pass-bys within 12 nautical miles of structures in the South China Sea because "it has been conclusively determined by the relevant international tribunals that nobody has a credible claim to sovereignty over them".
Conclusively, DCs play a relevant role both in the tumor microenvironment and systemic circulation, exerting differential pro-tumorigenic and anti-tumorigenic functions, which might be due to the plasticity of these cells capable of reacting to and integrating environmental signals.
One might ask if the studies would have been deemed more relevant if they had conclusively found that the oyster farm caused serious environmental harm.
Although the different conformation of the Gln271 side chain is a potentially interesting finding, currently, it cannot be conclusively determined whether this is functionally relevant because of the limited resolution of 1.9 Å [5] in the ASIC1 crystal structure at which N and O atoms are unlikely to be distinctly distinguished.
On the other hand, vaginal birth has been reported to result in damage to the pelvic floor and short-term urinary incontinence, but the causal link with clinically relevant symptoms is not conclusively proved [ 8, 31, 32].
These are intriguing and relevant phenomena, but none alone conclusively explains the problem.
Pancreatic cancer is difficult to conclusively diagnose without histological or cytological examination of relevant specimens and these specimens are often not available.
p4 The Dorus et al. findings (11) relevant to SHH and PAFAH1B1 do not conclusively show that positive selection, as opposed to relaxed constraints, for example, has occurred.
There is, therefore, perhaps the need for new and/or refined models to be developed and tested in order to conclusively demonstrate that exposure to magnetic fields at the relevant environmental levels neither induces molecular and genetic changes associated with leukaemia initiation, nor drives disease progression.
However, the observed change of magnitude in LINE-1%5mC levels cannot conclusively associate this observation to THM exposure and/or either could not be biologically relevant in terms of LINE-1 activation.
