Results were considered positive if at least two out of three methods utilized (RT-PCR, flow cytometry, or immunofluorescence microscopy) were conclusive.
TTL 324-residues isoform location into peroxisomes was already shown by fluorescence microscopy, and provided conclusive results regarding its import [ 8].
Since FAK staining requires MeOH fixation, confocal microscopy did not provide conclusive results as to the co-localization of diffuse total FAK and pFAK-Y861 observed in MOSE-L cells.
In summary, our study provides the first conclusive evidence, as shown by electron microscopy, that BACE1 resides predominantly within normal and dystrophic presynaptic terminals in wild-type and AD mouse model brain, consistent with our immunofluorescence microscopy of human AD.
Other approaches for cancer diagnosis based on cell morphology and microscopy (biopsies) are too not conclusive for early diagnosis of cancer.
Although not conclusive, high-resolution transmission and scanning electron microscopy revealed variant internalization behaviors where some of the SGS became folded and compartmentalized into tight bundles within cellular organelles.
Further ultrastructural analysis using transmission electron microscopy might well yield more conclusive findings.
The fluorescence microscopy data in Figure 6 are suggestive, but not conclusive.
Physical aspects of the sample are normally evaluated by Scanning Electron Microscopy (SEM), but it is in many cases unsuitable to provide conclusive chemical information about the distribution of the pharmaceutical ingredients in both layers and core.
Electron microscopy analyses of ghrelin in secretory vesicles, while revealing, would not provide conclusive evidence that ghrelin is actually secreted from the TCs during taste perception.
The recent medium-resolution cryo-electron microscopy structure of mouse Piezo1 revealed many features of the coarse channel architecture, but does not provide conclusive clues about the activation mechanism (Ge et al., 2015).
