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Caution is clearly warranted here about drawing any conclusions on causation on this or any other included factors, because an association at the PCT level does not guarantee that the association will hold at the individual level.
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The potential presence of unmeasured confounders prevented any conclusions of causation, even when sophisticated statistical methods were used.
To evaluate this point, we selected papers by authors of the Boffetta et al. (2008) commentary on topics with relatively few previous publications and lack of consensus on causation to assess how these authors describe conclusions from their own data.
But he denies that one need impose such a strong requirement on causation and causal explanation.
Further limitations are that the performed association analysis does not allow any conclusions about causation and that it is based on survey results that have not been validated by observation.
In conclusion, our systematic review, meta-analyses, and application of Bradford Hill's considerations on causation shows that there is no evidence of a causal link between estimates of knee joint loading during walking and structural progression of knee OA.
Studies such as this one, which rely on correlating one variable with another, are not enough to draw firm conclusions on their own, since correlation is not necessarily causation.
And the study is retrospective, so conclusions about causation and correlation are impossible to establish.
Her work on causation demonstrated reliance on ordinary language methodology.
(For Reid on causation and free will, see Yaffe 2004).
See the entry on 'Causation and Manipulability' for extensive discussion.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com