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This conclusion of the primary source of heat from advection also holds if we use monthly air-sea heat fluxes from the Global Ocean Data Assimilation System (GODAS 34,35 over the same time period (Supplementary Fig. 6).
Furthermore, our conclusion of the primary role of vascular role in the pathogenesis of muscular dystrophy does not deny or exclude the possibility of the currently accepted theory of "membrane vulnerability".
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Both confirmed the conclusions of the primary analysis (data not shown).
We carried out various sensitivity analyses to examine the robustness of the conclusions of the primary analysis.
These results confirm the conclusions of the primary evaluations and validate the use of 300IR tablets for clinical practice.
The results of the sensitivity analyses will be compared to assess the relative effect of missing data on the conclusions of the primary and secondary analysis.
Similarly, an equivalent analysis recoding deaths as 'non-revisions' did not modify the conclusions of the primary analysis (control risk 31.3%; ARR in favour of platelet-rich therapy 3.6%, 95% CI −10.0% to 17.2%, χ test; p=0.688).
The instrumental variable analysis did not alter the conclusions of the primary analysis for classroom based cognitive behavioural therapy compared with attention control (adjusted difference −0.82, 95% confidence interval −1.79 to 0.14, P=0. 09).
In the outlier analyses, the decline observed during period 2 for the primary analysis in the placebo → placebo group was not observed; however, the conclusions of the primary analyses that there was no significant difference in mGFR between tofacitinib and placebo groups at the end of the study was preserved.
The Monte Carlo method used in this analysis is considered highly reliable for evaluating the effects of a variable on the results of an analysis or on stability testing of results and conclusions of the primary analysis, and the large sample size used permitted the demonstration of high repeatability and statistical significance of the results.
Results of sensitivity analyses from the perspective of the public payer and the payer are presented in Tables 3 and 4. Sensitivity analyses evaluating the effects of age, control, HbA1C reduction, and discount rate for costs and effects determined no changes to the conclusions of the primary analysis with respect to cost efficacy and cost utility as a result of these variables.
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