Sentence examples for conclusion of dose from inspiring English sources

At the conclusion of dose escalation and after considering the overall toxicity profile, the recommended phase 2 doses of the combination using EWOC were sunitinib 37.5 mg PO daily and bortezomib 1.9 mg m−2 IV weekly, each given 4 weeks of 6. Anticancer drug development has evolved to include combinations of targeted agents without traditional cytotoxic partners.

As both the 95% confidence intervals contain 1.0, these data support the conclusion of dose-proportionality of ixazomib exposure over the ixazomib dose range of 0.5 3.11 mg/m (absolute dose 2.5 6.8 mg).

At the conclusion of dosing, appropriate tissues were harvested to measure safety parameters.

Only three of the included studies offered risk estimates for dose and frequency, making it difficult to draw conclusions of dose effect and frequency effect.

Lung function was measured every minute for 5 min after the conclusion of each aerosol dose.

Time was designated t = 0 upon conclusion of the loading dose.

However, the study population is large and diverse which makes it highly probable that the main conclusion of no significant dose differences between DET and GLAR in a once daily regime is representative for all T2D patients in Denmark.

However, it does not seem likely that there are differences between DET and GLAR patients with regard to compliance, and therefore this should not influence the main conclusion of no significant dose differences between DET and GLAR.

However, it is not likely that this would have changed the main conclusion of no significant dose differences between DET and GLAR as there are no compelling reasons to assume that co-morbidities differ between T2D patients treated with DET and GLAR.

Conclusion: Oral dose of one tablet of Sorbifer Durules per day is adequate for the maintenance of serum iron in normal range during recombinant human erythropoietin treatment in hemodialyzed patients.

In conclusion, the current evaluation of dose banding based on PK criteria confirms the feasibility of future implementation of this procedure in routine practice, and warrants its further evaluation in prospective clinical trials comparing the effect of BSA-dosing and dose-banding methods on toxicity and efficacy.