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A false positive is when we wrongly conclude an effect is present, when in reality there is no effect.
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Second, T2DM is a complex metabolic disorder caused by the interaction of multiple genetic and environmental factors; so gene-gene and gene-environment interactions should also be taken into account to conclude a true effect if possible.
As all retrospective analysis, one cannot conclude a direct effect of DPP4i on cardiovascular events, and only the on-going randomized studies could give a direct answer to this question.
Although our results suggest there is no effect of complex APOE haplotypes on cognitive function, we cannot conclude an absence of effect on cognition based on the low number of subjects in each group.
It is therefore impossible to conclude a causal-effect relationship between EGFR upregulation and fibrogenesis.
Concerning rilmenidine, which was dissolved in DMSO, it was not possible to conclude on an effect.
We conclude that an effect of BLL on risk of asthma for African Americans was not observed.
It would also be inappropriate to conclude that an effect on deaths prior to a specified number of hours or days necessarily implies that TXA works by reducing bleeding as opposed to reducing inflammation.
The first study to establish a role for dopaminergic neurotransmission during memory acquisition concluded a specific effect for aversive learning [89].
A meta-analysis of 104 studies also concludes a causation effect; the conclusion was based on longitudinal studies where health status deteriorates in times of unemployment, but improves in times of reemployment.
Although this set of experiments indicated a marked preference of Bcr/Abl for Erk2 activation and a correlation with IM resistance, they did not allow us to conclude a direct cause-effect mechanism yet.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com