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Given that it was not a randomised controlled trial comparing different loading regimens, we cannot conclude a direct causal relationship between the amikacin C max and the mortality rate.
Although this set of experiments indicated a marked preference of Bcr/Abl for Erk2 activation and a correlation with IM resistance, they did not allow us to conclude a direct cause-effect mechanism yet.
While this observation does not allow us to conclude a direct role of TBCC it suggests a possible involvement of TBCC in tumor aggressivity whether through microtubules or through other unidentified pathways such as interaction with the Arl2 protein.
As all retrospective analysis, one cannot conclude a direct effect of DPP4i on cardiovascular events, and only the on-going randomized studies could give a direct answer to this question.
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As Kenneth Clarke pointed out, a second election would almost definitely conclude with a direct repeat of the first result.
On the basis of our results we conclude that a direct perfusion bioreactor system is capable of producing clinically relevant volumes of tissue-engineered bone in a bioreactor system which can be monitored on line during cultivation and show bone formation after implantation in nude mice.
Conversely, the present observational study does not allow to formally conclude to a direct causal relationship between hookworm carriage, imbalance towards non-cytophilic antimalarial response and occurrence of malarial attacks, and does not exclude that genetic factors, for instance, could also contribute to either one of those 3 parameters.
The presence of MCPyV in Merkel cell carcinomas (MCC), its integration [19], [24] and its clonal mutation in the C-terminal region of the Large T antigen [25], merit further investigation both on the epidemiological and in vitro level in order to conclude in a direct oncogenic role of this polyomavirus according to the criteria of Harald zur Hauzen (detailed in [16]).
Thus we conclude that a direct involvement of SQSTM1 in the turnover of lipid droplets seems unlikely.
She concluded, with a direct plea: "We need you.
A recent report by the Commission on National Security, a bipartisan group set up by Congress, concluded that "a direct attack against American citizens on American soil is likely over the next quarter-century".
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