Exact(1)
Taken together, these modifications elicit a complex and concerted processing that greatly contribute to the chromatin remodeling and may drive different pathological conditions, especially cancer.
Similar(59)
The preparation of existing real-world datasets for publication as high-quality semantic web data is a complex task that requires the concerted execution of a variety of processing steps using a range of different tools.
Sensitivity of the mutants to RAL was measured in processing, strand transfer and concerted integration.
Taken together all those molecular differences found between assays could explain the few variations observed for 3' processing, strand transfer and concerted integration activity in term of inhibitor sensitivity.
To observe the effect of mutations Y143C and Y143R on IN activity and RAL sensitivity, the mutated integrases were produced, purified and in vitro 3'end processing, strand transfer and concerted integration were assayed according to standard procedures previously used in our laboratory [16], [21].
Wild-type (WT) IN and IN with mutations Y143C or Y143R were assayed in vitro in 3'end-processing, strand transfer and concerted integration assays.
The activities of 3'-end processing, strand transfer (ST) and concerted integration were compared to the wild-type one.
Viroid titer could thus be regulated by the concerted action of DCL and RISC, with DCLs processing the highly-structured genomic viroid RNA or some viroid dsRNAs arising from replication or from the action of host RDRs (in contrast to viruses viroids do not encode their own RNA replicases), and the resultant vd-sRNAs priming RISC and targeting additional viroid RNAs for degradation [2], [45].
The active and minimal quaternary structure of full-length IN for in vitro 3′-processing is a dimer, while at least a tetramer is needed for concerted in vitro strand transfer.
Surprisingly, the fine words prompted concerted action.
Obama and Gordon Brown urge concerted economic action.
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