Sentence examples for concerted dynamic from inspiring English sources

Together, these studies have suggested for the transport cycle in NSS proteins an allosteric process that is consistent with the alternating access mechanism32 in which concerted dynamic rearrangements on the extracellular (EC) and intracellular (IC) sides of the transporter result from ion- and ligand-specific conformational rearrangements.

This is especially true for enzymes following a bisubstrate kinetic, like Escherichia coli dihydrofolate reductase (DHFR) [1] and human 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1 or SDR28C1, according to the new nomenclature [2]; E.C. 1.1.1.62), where concerted dynamic motions are necessary between the enzyme conformations responsible for specific kinetic steps.

Computational inference methods on global gene expression data suggest that more than 80 predicted DNA binding proteins work together to bring about a concerted, dynamic gene expression response to neutralize ROS toxicity and repair macromolecular damage [ 11].

Nevertheless, the inhibitory effect shown in the present article may not reflect a simple excess of substrate-targeting modules, which may impede the dynamic and concerted action of the two enzymes on the substrate.

The development of mdDA neurons is a tightly controlled and highly dynamic process requiring concerted action of both extrinsic and intrinsic signals during different stages of development.

Therefore, the dynamic of the concerted evolution process depends on two conflicting forces: the homogenizing forces and the forces which generate variability [ 58].

We present the dynamic mechanism of concerted motions in a full-length molecular model of the human dopamine transporter (hDAT), a member of the neurotransmitter/sodium symporter (NSS) family, involved in state-to-state transitions underlying function.

With over one billion global Facebook users, there is emerging evidence that activists are making concerted efforts to utilize Facebook's dynamic ability for addressing social issues.

Glycosylation is a dynamic process involving a concerted interplay between various glycosyltransferases and associated enzymes in the endoplasmic reticulum and Golgi apparatus [18].

As a flipside of the dynamic character of the concerted evolution process, the het-d and het-e incompatibility genes appear to be genetically fragile.

My analysis of the Rsp satellite DNA family demonstrates that Rsp: 1) exists outside of the large block of pericentromeric satellite in locations across the D. melanogaster genome; 2) exists in species of the melanogaster group; 3) shows evidence for concerted evolution; and 4) is evolutionary dynamic in its abundance and genomic distribution over short evolutionary time scales.