Sentence examples for concerted changes in from inspiring English sources

In one of the simulations, structural relaxation after the removal of regulatory ions led to concerted changes in the tilt of the pore helices, resulting in iris-like dilation and spontaneous hydration of the hydrophobic neck.

A new conductance analysis method applied to intracellular recordings in the somatosensory cortex of anesthetized rats revealed mirror changes of excitation and inhibition during the up- and down-states of slow waves, but concerted changes in conductance variances.

Put together, these data suggest that concerted changes in the conformation of specific residues facilitate the stabilization of nucleotide complexes thereby enabling the steps involved in the ping-pong reaction mechanism without large changes to the overall structure of this enzyme.

ErbB kinase-conserved residues in JM-kinase linker and β2-β3 loop also undergo concerted changes in the inactive dimer.

These studies define overlapping and distinct modes of CREB and ATF1 regulation by phosphorylation that may ensure concerted changes in gene expression mediated by these factors.

Co-expression network analysis is based on the idea that large collections of microarray data contain information about concerted changes in transcript levels.

Similarly, in another example, GNAS is differentially expressed in all nine cases, with a subset of cases showing concerted copy number change while the remaining cases reveal concerted change in DNA methylation.

Next, we further refine this subset of genes from step 2 by selecting those having concerted change in all dimensions in the same sample which we term as MCD.

We hypothesize that regulatory mechanisms under water deficit induce a concerted change in metabolism that allows the cell to cope with the new condition and that leads to more dependent metabolic profiles.

The use of independent rate priors to take into account concerted change in rate-variable molecular dating has thus far never been applied, and would rely upon identifying correlates of molecular rate that may have varied systematically across the phylogeny [ 22, 32].

Coupling free energy in the absence and presence of changes elsewhere in the molecule is discussed in terms of specific folding models, including stepwise folding and concerted changes.