Sentence examples for concerted binding from inspiring English sources

Concerted binding to the methylated histone tail and nucleosomal DNA underlies the high- affinity, specific recognition of H3K36me nucleosomes by the PSIP1-PWWP domain.

Superposition of homologous PWWP domains onto the structural model of the complex shows that these domains all share similar configurations of an aromatic cage and basic patches that potentially enable concerted binding to both methylated H3K36 side chain and nucleosomal DNA.

Through the continuous conformational changes of the ARP module, the nucleosome substrate could be engaged on the ATPase catalytic core and promote concerted nucleosomal binding.

At that point, a new FPP molecule binds, while the farnesylated protein remains bound, followed by product dissociation either prior to or concerted with binding of a new CaaX-box substrate protein.

The process is initiated by concerted ATP binding to a GroEL ring, rapidly followed by initial contact with GroES, and concludes with additional rigid-body movements of the GroEL apical domain to form the GroES-domed chamber.

Reorganization of the actin cytoskeleton during migration is an essential process involving concerted action of several actin binding proteins and the exclusion of adhesion related molecules to the rear end [8], [10].

We previously demonstrated in a mouse embryonic carcinoma cell model that an endogenous dominant negative RARα mutant, lacking part of the E domain harboring the RA-binding domain, induced concerted epigenetic repression of both RARβ2 and CYP26A1, encoding for a RA hydrolase involved in RA catabolism [8].

To date, a survey of the concerted evolution of miRNAs and their binding target sites has been investigated in Arabidopsis (Ehrenreich and Purugganan 2008), and rice (Wang et al. 2010), respectively.

Some DNA binding proteins also show concerted regulation upon salt treatment.

It took concerted effort to stand back.

The SH3 and SH2 regulatory domains of SFKs are believed to act in a "snap-lock" fashion, where intramolecular binding of one domain causes concerted engagement of the second domain.