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In the present study, we investigated if the release of exosomes from pancreatic beta-cells can affect the surrounding cells and can constitute a cell-to-cell communication mode permitting a concerted adaptation of beta-cells to environmental cues.
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Furthermore, the enzyme-ligand (both NADPH and E1) motions observed in our MD study suggested a preferential pathway for this kinetic cycle, with the cofactor NADPH entering first, followed by the substrate E1, which then induces concerted enzyme adaptation to both ligands.
Given that the phenotypic variation in Petrocosmea mainly involves floral rather than vegetative traits, the diversification of Petrocosmea is likely a product of concerted evolution associated with adaptation to different groups of pollinators rather than a direct response to physical environmental variables.
The emergence of new technologies, including computers, the Internet and related adaptations, is creating situations, which require concerted action within national and regional space.
Differing views have emerged as to the role of gene duplication in driving evolutionary novelty, including concerted evolution in tandemly repetitive families, mediating genetic robustness, subfunctionalization, and neofunctionalization de novo or involving pre-adaptation [ 3- 7].
Surprisingly, the fine words prompted concerted action.
Obama and Gordon Brown urge concerted economic action.
It signifies concerted effort by the caller.
It took concerted effort to stand back.
What we need is concerted will.
Simultaneously balancing all aspects requires concerted effort.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com