Sentence examples for concerted activation of from inspiring English sources

Likewise, midgut hyperproliferation in response to ectopic Wg signalling requires Myc and involves concerted activation of EGFR and JAK/Stat (Cordero et al, under review).

This concerted activation of the proteases highly relevant for countless signaling systems, may be one major reason for the different transcriptomic responses that can be seen both in the trachea and the salivary gland following identical experimental stimulation protocols.

Cell stimulation triggers concerted activation of these molecular sets that produce a spatio-temporally organized transient increase in the [Ca2+]i (cytosolic/intracellular Ca2+ levels), which is sufficient and necessary for the engagement of Ca2+-sensitive effectors protein(s) of the secretory machinery.

Thus, the concerted activation of both Toll-like receptors and C-type lectin receptors is required for IRF1-mediated IRGB10 regulation, which is a key event governing ligand release and inflammasome activation upon A. fumigatus infection.

Systemic acquired resistance (SAR), an inducible plant-defense response to local infection, requires the signaling molecule salicylic acid (SA) and the transcriptional coactivator NPR1, with concerted activation of pathogenesis-related (PR) genes.

This represents a complementary view of the acid growth mechanism in which a concerted activation of the plasmalemma and tonoplast H+ pumps plays a key role in the root cell expansion process, which is driven by environment-derived molecules endowed with auxin activity, such as HS.

Moreover, under resting conditions, brief elementary events of Ca2+ release ("Ca2+ sparks") arise as a result of the concerted activation and deactivation of six to twenty RyR2 in brief bursts lasting ∼5 20 ms [9], [10].

The process by which myeloid progenitor cells differentiate into monocytes and eventually into fully mature macrophages requires the concerted activation and repression of several lineage-specific genes such as PU.1, GATA2, and c-myb, among others.

Moreover, biochemical analysis of the PDZ-gated channel combined with sporulation assays reveal that activation of the SpoIV RIP pathway is induced by the concerted activity of CtpB and a second signaling protease, SpoIVB.

Bone homeostasis depends on the concerted activities of bone cells.

The lack of significant changes on the cellular representation of mtDNA in liver cells during cellular proliferation suggests that mtDNA and nDNA synthesis is coordinated and supports a concerted trans-activation of the replication of both genomes [52].