Judy Lewis, it emerged, had kept house for Bob Dylan during his surrealist, acid-rock, Isle-of- Wight-concert phase.
Mathematically though, this result found here and in [1] may find explanation by invoking some interactions between the origination and extinction time series that in concert (with phase coherence) produce more significant periodicity.
Several Hippo pathway components may thus regulate (independently or in concert) S-phase progression and quality control and thereby safeguard genomic integrity.
Our observations, performed at five time points during the period from fruit set through the end of exponential fruit growth, indicate that this is a dynamic period of cucumber fruit development involving an array of internal and external morphological, physiological, and transcriptomic changes that act in concert with phases of active cell division, expansion, and response to the environment.
Two papers published today present the first evidence for clocks independent of the circadian one: a sea louse whose swimming patterns sync up with the tides, and a marine worm that matures and spawns in concert with the phases of the moon.
It is known that the initiation of both DNA replication and histone biosynthesis in concert with S-phase entry stringently requires cyclin E/CDK2 (reviewed in [ 4]); however, the coupling of histone expression to DNA synthesis following S-phase entry seems to be regulated by factors other than cyclin E/CDK2 [ 42].
Alternatively, if EPP and cessation of laying are not linked in concert to laying-phase incubation, we expect that females will respond to the removal of the egg stimulus by laying more eggs but without an increase in the number of EPO, leading to proportionally fewer EPO in larger clutches.
During nutrient depletion, sustained expression of CLN3 which is normally downregulated under these conditions also increases the frequency with which cells growth arrest in S phase in concert with a shorter lifespan and age-dependent increases in genome instability and apoptosis.
Because transcripts of lasR, rhlR, and rpoS increase at the onset of stationary phase in concert with activation of most quorum-controlled genes [ 8, 15], it is possible that the abundance of the encoded proteins is critical for target gene induction.
Plk1 does not appear to phosphorylate Eg5 in vitro (Hochegger Laboratory, unpublished results), and Plk1 inhibition does not appear to affect the phosphorylation of Eg5 at Thr927 but controls accumulation of pericentriolar material in G2 phase in concert with interphase Cdks.
The concert worked through five phases, not strictly chronological but drawn from the mood of the songs and the choreography of their videos.
