There are several methodologic concerns in studies of this nature.
There are particular methodological concerns in studies of drugs in relation to diabetes where published guidelines prescribe a stepwise treatment approach usually starting with metformin.
As far as hippocampal activation is concerned, in study 2 we found a stronger activation in the right hemisphere, as opposed to an enhanced activation observed in the left hemisphere in study 1.
Another concern in study design was seasonal migration of the UAE population.
Bullying in school has long been a concern in studies in the West.
Factors that contribute to variation in nectar sugar composition, nectar concentration and volume have been a central concern in studies of pollinator assemblages in angiosperms.
A major concern in studies using cultured primary neurons is that differences in culture conditions, handling procedures and stimulation paradigms will cover the real dynamics of nucleocytoplasmic shuttling in response to synaptic activity.
Multiple testing is a major concern in studies of genetic epidemiology.
However, heterogeneity is always a concern in studies of human tumour tissue.
It is also of particular concern in studies that focus on symptoms.
