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Although it has been reported that T cells expressing constitutively active Akt still require antigen stimulation to grow [ 11], transducing constitutively active Akt raises safety concerns for the application of this strategy.
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Based on the mobility control function, the viscosity loss is the first concern for the application.
Because of his concern for the application of mathematics, Poincaré did not confine himself to the perfect purity of mathematics.
These results raise concern for the application of multimedia design theory to classroom practice.
A concern for the application of LPF is the formation of an oil film on the wall (Nunez et al. 1998; Saniere et al. 2004).
It should be noted that a recent meta-analysis suggested that safety aspects of heparin in sepsis are underreported, and we conclude that risk of bleeding is a potential concern for the application of heparin in this setting [41].
Immunological tolerance to normal proteins expressed at low levels in normal tissues and overexpressed in tumours (e.g. HER2/neu) is a concern for the application of these TAAs in immunotherapy [ 9].
In addition, the lifelong latency and ability to re-infect, despite pre-existing natural immunity, represent a significant safety concern for the application of attenuated live vaccines [ 4, 16].
With the growing market for context-aware applications, energy requirements of such applications have become one of the major concerns for the mobile application developers.
Due to the corrosive nature and the high diffusivity of lithium, the corrosion attack on the seal and the physical permeation of liquid lithium through the seal are two main concerns for the proposed application.
At the same time, the prevalence, severity, and overall burden of morbidity and mortality represented by mental disorders reflects an urgent global public health concern ripe for the application of epidemiology.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com