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Such insight would aid more effective risk assessments concerning these compounds, while also improving molecular design.
There are no comparable data in the literature concerning flavone intake in relation to breast cancer risk so, at this stage, our findings concerning these compounds should be considered as hypothesis generating rather than as documenting a genuine association.
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Data on the potential use of epigenetically active compounds concerning these pathologies are, in fact, merely provisional.
Concerns about these compounds have also led to an interest in complementary and alternative methods of preventing or treating MDD.
Toxicity associated with high doses of water-soluble antioxidants such as ascorbic acid are less of a concern, as these compounds can be excreted rapidly in urine.
The prevalence of PBDEs in human tissue is of concern because these compounds are known to alter behavior, thyroid-hormone signaling, and sexual development in animals.
Concern that these compounds may be human carcinogens has prompted us to develop immunochemical methods for quantifying these compounds in the human diet and for identifying the parent compounds and metabolites in urine and feces.
The high levels of PBDEs in the human population, especially in infants and toddlers, are of vast concern because these compounds are chemically similar to PCBs and have been shown to be developmentally neurotoxic in rodents.
Toxicity is a major point of concern with these compounds when administered to body cavities, but NCT seems to be well tolerated in the bronchopulmonary system according to our results.
In particular, the frequent occurrence of resistance to quinolones is a matter of concern because these compounds are often used for first treatment of serious human infections, before the results of susceptibility testing are available.
The high level of PBDE contamination in the U.S. population and food is cause for concern because these compounds are chemically similar to polychlorinated biphenyls (PCBs) and have been shown in laboratory animal studies to be toxic in a number of ways.
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