Sentence examples for concerning mutation from inspiring English sources

4 7 However, data concerning mutation frequency of the RAS mutations other than KRAS exon 2 are very limited.

Concerning mutation analysis, the MLPA assay was performed in 42 of 45 cases (3 cases were not studied due to low quality DNA).

The similarities and difference between these two yeast species allowed us to make several a priori predictions concerning mutation rate and spectrum in Sc. pombe.

Although these problems have already been discussed in previous publications (54 56), the current situation concerning mutation databases and their heterogeneity is still an acute problem due to the exponential growth of data generated by genome sequencing.

Concerning mutation status, patients with EGFR mutations had a median OS of 14 months (CI 5.1 22.9), while patients who were EGFR-M negative had an OS of 12 months (CI 0.6 23.4) (the log rank test was not conducted because of the small number of mutation-positive patients (n = 4)) (Table 2 and Figure 2(a)).

However, Eggan and McCarroll emphasized that now that this phenomenon has been found, inexpensive gene-sequencing tests will allow researchers to identify and remove from the production line cell cultures with concerning mutations that might prove dangerous after transplantation.

Data concerning mutations in HPRT and G6PD genes, analyzed here in two different colon tumours and nearby normal intestinal tissues of two male patients, lend support to this hypothesis.

If using the therascreen® BRAF Pyro Kit for the detection of additional mutations the results should be critically considered especially concerning mutations in codon 597, 596 and 594 of the BRAF gene.

In contrast to the scant information concerning mutations affecting mature miRNAs, polymorphisms in the binding sites for miRNAs have been reported to a larger extend (see, for instance, [ 21, 22]).

More recently, research concerning mutations of avian H5N1 influenza that could allow it to be transmitted among mammals via aerosols has sparked immense controversy (Berns et al., 2012), highlighting the threat influenza A viruses pose and the need to better understand their interaction with the human immune system.

As far as NPM1 is concerned, mutations in this gene drive tumorigenesis in acute myeloid leukemia (AML) [ 60- 62], but its role in solid tumors has been controversial [ 63- 65].