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All analyses were based on published data, but study authors were contacted, if necessary, for further clarifications that concerned study eligibility.
The ICRL investigated with the concerned study site the possible causes of these errors.
When discordant results were reported, training on use and interpretation of the rapid test was reinforced at the concerned study site(s).
In working practices, the site monitors where interested in aspects that facilitate coordinated execution of the concerned study including effective communication throughout the study team, updates on any new findings about the study, study coordination and how study staff relate to each other.
26 The data concerned study design, evidence level, 27 study size, inclusion and exclusion criteria, outcomes, results, as well as study strengths and limitations, especially the risk of bias and confounding.
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However, traditionally, the concerned studies are performed separately for different objectives and difficult to perform an overall evaluation.
The present review concerned studies conducted after the publication of the IHS (1988) and ICHD-II criteria [17, 41].
About two thirds of the papers described a study in which a SNOMED version was the primary subject of study while the remaining one third concerned studies in which SNOMED plays a secondary role.
As far as assessment of anxiety and depression in breast cancer patients is concerned studies have shown that the HADS may result in under estimation of psychiatric morbidity among women with early stage breast cancer and therefore its utility for screening purposes in early stage breast cancer patients is limited [ 11, 12].
In addition, higher EI would not have been as necessary in the first-year students who might be less concerned with study because studying medicine was not their own intention or who had been overly disappointed with teacher's quality (see Table 1) [ 11].
Thus, this paper reports a systematic mapping study to overview the development of semantics-concerned studies and fill a literature review gap in this broad research field through a well-defined review process.
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