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The risk for TB among health care workers in developing countries is well recognized (12 ) but has become more of a public health concern with evidence of the nosocomial transmission of MDR and XDR TB in South Africa.
All economic variables specified as outcomes in these Cochrane reviews imply a concern with evidence related to the distribution of costs (or resource use) associated with the interventions being studied, as opposed to evidence on cost-effectiveness.
More than a third of cancers are diagnosed in people aged 75 years and above, but low UK survival rates for older people have in recent years been identified as a matter of significant concern, with evidence suggesting a range of causative factors.
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The review is mainly concerned with evidence of how the approach could be improved through 'the exploration of key aspects of the flipped class that influence its effectiveness and contribute to an improved student flipped learning experience' (p. 86).
The evidence synthesised here is important to a broad sweep of institutions concerned with evidence uptake in general and systematic review uptake in particular.
The practical linkages with national health agendas had their roots in UNICEF-sponsored work in Nicaragua and Honduras in the mid 1980s, concerned with evidence on key child and maternal health outcomes [ 78, 79].
This research used ERG reports and clarification letters as sources of information to identify common issues and concerns with evidence submissions from manufacturers as part of the NICE STA process.
The method is also of interest to professionals concerned with "evidence-based practice".
Scotland Yard's record keeping on its own investigations into police corruption were a cause of concern, with key evidence the subject of mass shredding in 2003.
Thromboxane A2 unopposed by prostacyclin in individuals with increased risks of cardiovascular thrombosis is a concern with enough evidence to be reflected in an FDA-mandated recent label change for rofecoxib.
To identify factors associated with the decisions of the Federal Department of Home Affairs concerning coverage with evidence development (CED) for contested novel medical technologies in Switzerland.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com