Sentence examples for concern regarding the method from inspiring English sources

One concern regarding the method is that its power relies on a small number of loci being true associations (see Supplementary Figure 8 of [ 3]); that is to say, the number of differences due to the phenotype of interest is small (<1% of sites tested).

One concern regarding the methods and design is that the authors appear to have used a separate wild-type mouse colony and compared them to ephrin-a2 KO mice inbred via a backcrossed colony.

As you will see one reviewer was enthusiastic about the work and recommended publication; however, the other two reviewers, while agreeing that the work was potentially important, raise significant concerns regarding the method you describe.

However, recent efforts in lemur species delimitation have raised concerns regarding the methods and data used for the diagnosis of species-level lineages [ 12].

However, there was a high concern regarding the various arbitrary methods by which the cut-off threshold for 9p deletion was decided in studies especially in those studies using I-FISH as the main technique [ 29, 32].

While reporting this prevalence, however, the authors expressed their concern regarding the considerable variation in methods and instrument used across studies included in the review.

The results of these analyses raise a concern regarding the validity of virtual screening methods that use ligands in local minimum conformations.

The results of these analyses raise a concern regarding the validity of virtual screening methods that use ensembles of local minimum conformations of both ligand and receptor to address molecular flexibility according to the conformation selection theory [6].

From a structural mechanics point of view, an important concern regarding the effectiveness and safety of this method is the potential of brittle debonding failures.

I concern regarding the predictive power of TFSVM methodology, performance of the method, biological significance of predicted targets, interpretation and extrapolation of the results, and independent validation.

Some currently available test methods are sufficient to raise concern regarding the potential endocrine-disrupting properties of some substances.