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compared to established thresholds of toxicological concern in absence of safety data or structural analogs.
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However, the reliability of these survey instruments in predicting exposures to chemicals of concern in the absence of actual exposure measurements is uncertain, and they should be used cautiously.
Although this did not reach grade 3 and appeared to be reversible on stopping the drug, it was unexpected and of concern in the absence of a clear explanation.
This is of particular concern in the absence of available alternative chemotherapeutic agents.
This could be of particular concern in the absence of blinding if more favourable assessments were made towards their preferred treatment.
However, for patients with low-lying tumors treated with total mesorectal excision, the primary concern in the absence of lateral or inguinal lymphatic metastases is distal intramural spread.
Following international standards concerning energy performance of buildings, in absence of reliable data on the envelope characteristics, thermal transmittance of building elements should be measured in situ.
This data will contribute to in-depth investigations concerning the mechanisms the maintain Hox colinearity in absence of a coordinated genomic organization.
Since extreme weight or shape concerns in the absence of eating disorder behaviours are more common than the combination of concerns and behaviours, it is not surprising that body dissatisfaction emerged as the stronger predictor of impairment among underweight participants.
Fox said that he was "deeply concerned" in the "absence of evidence [how] four unsubstantiated claims can attract publicity of such magnitude".
The rationale for restricting advertising was that these drugs raise consumer concerns in the absence of screening for safety and effectiveness.
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