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While its inclusion may be potentially viewed with concern (as it is not a diagnostic criteria of IBS-D), from phase I onward a considerable number of patients mentioned that they would occasionally experience constipation.
Privacy is just as much an American concern as it is a European one.
Hezbollah's presence has become a source of concern as it is recognized by counterterrorist experts to have some of the most dangerous operatives in the world.
"The manufacturing industry might cause most concern as it is a pillar of China's economy," said Li Huiyong, an economist at Shenwan Hongyuan Securities in Shanghai.
The corresponding figures for PrEP are much better: while adherence is a concern, as it is with condoms, Truvada offers H.I.V. protection that is more effective than any other method short of abstinence.
Of course, the workload is a concern, as it is in families up and down the country struggling to make ends meet in the recession, and paperwork doesn't seem to be being reduced, in spite of election promises.
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He was a spectral presence at this week's NATO summit, where Russia seemed almost as pressing a concern as it was in the days of the Soviet Union.
In particular, the effect of the Ilizarov device on adjacent joints during distraction is of concern as it was shown to increase the pressure on articular cartilage.
The selection bias introduced as a result of the non-random sample was not of much concern as it was not intended to generalize the estimated percentage of drivers (with impaired driving ability etc).
Having a decent augmented reality headset like the HoloLens suggests that it's as close to being a mainstream concern as it's ever been.
The apparent lack of timekeeping equipment was not a cause for concern as it was assumed each man had his own watch.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com