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We conceptualized the trial as two linked sub-studies, one focusing on patients with significant depressive symptoms (Patient Health Questionnaire-9 [PHQ-9] scores ≥ 5) [ 45], the other on patients with few or no depressive symptoms (PHQ-9 scores < 5).
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DR, LT, GD, JS conceptualized the initial trial design.
Nevertheless, we argue here that this is not the correct way to conceptualize the SUPPORT trial interventions.
Insofar as the norms of clinical practice have been violated in this way, there is strong justification for conceptualizing the SUPPORT trial interventions as research.
With this framework in mind, we can then ask: what arguments might be proffered in favor of conceptualizing the SUPPORT trial interventions as practice?
Indeed, it is evident that Lantos, the SUPPORT trial investigators, and the 22 research ethics committees that approved the trial, appear to have conceptualized the low- and high-oxygen saturation interventions in precisely this way, that is to say, as clinical practice.
Originally we conceptualized the PP intervention of the BETTER Trial as only an internal practice facilitation intervention.
conceptualized the study.
T. Zhang and Y.H. conceptualized the project.
M.O. and D.T. conceptualized the study design.
ESY and ACS conceptualized the article.
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