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There are many options for IFE concepts — target irradiation, target heating, drivers and reaction chamber.
The team defined the concepts, target population and outcomes of interest, and has drafted three main research questions for the scoping review.
Based on the original data source for each group of concepts, the concepts were grouped into the following categories: functional annotations, literature derived concepts, target sets, interactions, metabolite-centered concepts and chromosomal location (Cytoband) (Additional file 1: Table S1).
The York framework suggests a broad, clearly articulated research question, defining concepts, target population, health outcomes, and scope whilst accounting for the aim and rationale of the review (Arksey and O'Malley 2005; Levac et al. 2010).
Whereas understanding basic PKPD concepts (target site exposure, occupancy, and modulation) can enhance the confidence in the compound, systems pharmacology can increase the understanding of efficacy and adverse events in specific diseases and patient populations.
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This review aims to give an overview of current and novel concepts targeting the virus and the host for managing influenza.
Furthermore, we evaluate a possible correlation between EMT marker expression and patient prognosis as well as current therapeutic concepts targeting the EMT process to slow down or prevent metastatic spread of malignant tumors.
Second, x-phi supplies valuable data about the concepts targeted for explication.
We do not assume that this increased performance is a direct measure of increased student understanding of the concepts targeted by the activities.
Although the list of concepts targeted is by no means exhaustive, we focused on the core concepts generally considered essential to undergraduate instruction in evo-devo (Hiatt et al., 2013).
Two types of evidence from our surveys support this claim: 1) the concepts targeted by the questions that elicited the lowest correct response rates and 2) the relative prevalence of different types of conceptual difficulty.
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CEO of Professional Science Editing for Scientists @ prosciediting.com